This sector includes biotechnology, pharmaceuticals, research services, home healthcare, hospitals, long-term care facilities, and medical equipment and supplies. Companies in this sector include Astra Zeneca, Pfizer and Roche Holding.
Amgen takeover of Nuevolution provides rare valuation for preclin immune/inflam assets US giant Amgen has announced an agreed takeover offer of SEK1.6bn (c$167m) for Nuevolution, a Swedish biotech, in a move which puts a monetary value of a small number of orally available preclincal assets, mostly in the immune/inflamamtory space. This area has seen relatively few […]
Syncona’s Blue Earth gets good results in prostate cancer diagnosis – Syncona has a large stake in Blue Earth Diagnostics. Blue Earth has been testing its prostate cancer diagnosis at a university hospital in Germany. The test (a radiohybrid PSMA-targeted agent, rhPSMA-7) for high-risk primary and recurrent prostate cancer was bought by Blue Earth in […]
Sareum (SAR), together with its US-based licensee Sierra Oncology, should be a major beneficiary in competitive terms from an apparent decision by Lilly to discontinue development its Chk1 inhibitor, prexasertib. Sierra has the only other compound with this mechanism in clincial trials and, as a result, its Chk1 inihitibitor, SRA737 – which originated at Sareum […]
Syncona establishes retinal gene therapy platform – Syncona has announced the merger of two of its companies, Gyroscope Therapeutics (Gyroscope), an ophthalmology company developing genetically defined therapies for retinal diseases and Orbit Biomedical (Orbit), a specialist medical device company focused on precision sub-retinal therapeutic delivery. Syncona will own 82% of the enlarged company (a holding value […]
Sareum (SAR) has noted the presentation by its partner Sierra Oncology of preclinical data showing “profound synergy” for the triple combination of the CHK1 inhibitor SRA737 in combination with low-dose gemcitabine (LDG) and anti-PD-L1 immunotherapy in a mouse model of small cell lung cancer (SCLC). The data were reported in a late-breaking oral presentation at the […]
Syncona/Woodford investment Autolus reports positive data – Claire Roddie MB, PhD, FRCPath, honorary senior lecturer, Cancer Institute, University College London, has presented initial data from the ongoing Phase 1/2 trial of AUTO1 in adult acute lymphoblastic B cell leukemia (ALL). the presentation was made at the American Association of Cancer Research Annual Meeting 2019 in Atlanta, […]
Bellevue fund manager Dr Daniel Koller to step back from BB Healthcare – Dr Daniel Koller, head of investments at Switzerland-based healthcare specialist, Bellevue, is to scale back his involvement with BB Healthcare Trust (BBH) and focus on the core Zurich-based BB Biotech AG (BION) company. Dr Koller’s Step back from BB Healthcare is a planned […]
Biogen Alzheimer’s failure drags down Biotech Growth – Biogen, a key holding in Biotech Growth Trust and a component of most other biotech and healthcare portfolios, has lost a third of its value after trials of an Alzheimer’s drug failed to show any benefit. Biogen and its partner, Japanese drugmaker Eisai, said they would stop […]
Primary Health Properties to acquire new Kew medical centre for £4.6mn – Following its merger with MedicX Fund, Primary Health Properties (PHP) has announced that forward funding is in place for it to acquire a new primary healthcare medical centre in Kew, London. The property is due to be completed in October 2019 and will […]
New shares in Primary Health tradeable following MedicX merger – following on from the announcement on 14 March 2019 by MedicX Fund Limited and Primary Health Properties (PHP) that their merger had become unconditional in all respects, PHP announced that dealings in the new shares became effective at 8.00 a.m. today (March 15, 2019). The […]
Wellcome Trust charity cuts stake in Syncona – Wellcome Trust Limited, a UK biomedical charity, has confirmed that it has sold approximately 57 million ordinary shares in Syncona Limited (SYNC). This represents approximately 8.7% of Syncona’s issued ordinary share capital. The shares were sold at 245p per share, equating to gross proceeds of approximately £141m for […]
Syncona shifting funds into cash – Syncona is changing the way it invests the portion of its portfolio that is not committed to biotech investments. It says: “Over the last two years, Syncona has evolved the investment parameters of its strategic capital pool to focus on liquidity and capital preservation in order to support Syncona’s […]
Primary Health Properties (PHP) has announced that it has contracted to acquire a The Meath Primary Healthcare Centre, in Dublin 8, for a total cost of €10.9 million. The transaction is being conducted through Primary Health Properties ICAV, an Irish investment vehicle that is wholly owned by PHP. This acquisition, which has a completion date […]
Caledonia Investments acquires minority stake in BioAgilytix – Caledonia has invested a minority stake in US-based pharmaceutical services business BioAgilytix, which specialises in bioanalytical testing solutions for molecule research and development. Caledonia has invested alongside Cobepa (a Belgium and US-based investment company), which it has a 5% shareholding in. BioAgilytix has offices in Raleigh, North […]
Symphony International suffering, NAV and share price decline sharply – Symphony International Holdings has realised a substantial loss on both share price and NAV in their 2018 results. NAV declined 24% in 2018, moving from $1.27 per share to $0.96 per share, a roughly 24% decrease. This comes as a result of one of the […]
Syncona’s Nightstar Therapeutics to be acquired for $877m – Syncona Limited founded Nightstar Therapeutics in 2013, with an original investment of £56.4m. Syncona’s holding of Nightstar at the time of sale was £254.6m, a £135.4m uplift previous valuation. This results in a 4.5x multiple on Syncona’s original investment and an internal rate of return (IRR) […]
Syncona funds new immuno-oncology company – Syncona is contributing CHF 28 million (GBP21.4 million) to a CHF 35 million (GBP26.8 million) fundraising being carried out by Anaveon, a new immuno-oncology company. Syncona will have a 47.0 per cent stake in the business. Anaveon was founded in December 2017 by leading experts in the field of immunotherapy, […]
BB Healthcare Trust has announced its annual results for the year ended 30 November 2018. During what the trust’s chairman, Professor Justin Stebbing, describes as “another successful year”, the trust provided Nav and share price total returns of 24.0% and 21.6% respectively. These returns are ahead of the MSCI World Healthcare Index, which it says […]
Primary Health and MedicX to merge – The boards of Primary Healthcare Properties (PHP) and MedicX Fund have reached agreement on the terms of a recommended all-share merger between MedicX and PHP, which is intended to be structured as PHP acquiring the entire issued and to be issued share capital of MedicX. Under the terms of […]
WWH opens new positions in Takeda and Novartis Orbimed-managed Worldwide Healthcare Trust (WWH) has disclosed new substantial shareholdings in Takeda – the Japanese pharmaceuticals group that has just completed a takeover of Shire Pharmaceuticals – and Novartis, according to an analysis by Marten & Co. The shareholding in Takeda appears in third place and accounts for […]
BPCR boosted by windfall profit on Tesaro loan BioPharma Credit (BPCR), the LSE-listed investment vehicle that specialises in providing loans to biotech companies, is to receive a windfall profit from the early repayment of a $500m loan (of which it provided 64%) to Tesaro last year. This follows the completion of the acquisition of Tesaro, […]
QuotedData join the Master Investor Show 2019 main stage line-up – QuotedData is, once again, a key sponsor for the Master Investor Show. Edward Marten, QuotedData’s CEO, shall join the Main Stage line-up on Saturday, 6 April, at London’s Business Design Centre. We’d love to see as many of you as we can at the event. […]
Polar Capital Global Healthcare let down by widening discount – Polar Capital Global Healthcare reports that its NAV rose by 19.8% over the year end of September 2018 on a total return basis, ahead of its benchmark, the MSCI ACWI Healthcare Index, which returned 17.2% over the same period. However, a widening in the discount to NAV […]
BB Healthcare announces result of issue- BB Healthcare Trust plc (BBH) announced today that they have successfully raised gross proceeds of approximately £46.3 million from an initial placing, offer for subscription and intermediaries offer of ordinary shares. The net proceeds of the initial issue are approximately £45.4 million. They raised the money through the issue […]
International Biotechnology benefits from narrowing discount – International Biotechnology has reported that, over the year ended 31 August 2018, its NAV laggeded the NASDAQ Biotechnology Index (NBI) a little, returning 8.6% versus the NBI return of 10.1%. A narrowing discount meant that shareholders saw a total return of 13.7%, however. The biotech sector outperformed the UK equity market over […]
Caledonia selling Choice Care Group – Caledonia Investments is selling Choice Care Group, a provider of residential and supported living services for people with learning disabilities and mental health conditions, to iCON Infrastructure Partners, IV L.P., a fund advised by iCON Infrastructure LLP, an independent infrastructure investment group with approximately EUR2.5bn of assets under management. Choice was […]
BioPharma Credit extends loan to Amicus – BioPharma Credit (BCPR) has entered into a $150m, five-year loan agreement with Amicus Therapeutics, a US-based biotech focused on rare disease. The senior secured loan will have a 2.0% additional consideration and bears interest at Libor plus 7.5% subject to a floor of 1% and certain caps. The loan is interest […]
Malin achieves small increase in fair value of investments Dublin-listed biotech VC investor Malin (ISE:MLC) achieved a marginal increase in the fair value of its investment portfolio in the first half of 2018, with gains on its four largest investments set against write-downs on smaller ones. This fair value, which was struck in accordance with […]
IBT-investee Sangamo set to disclose gene edited drug data US biotech Sangamo Therapeutics (Nasdaq: SGMO), a mid portfolio but recently enlarged holding for the UK-listed International Biotech Trust (IBT), is set to report the first clinical data from its SB-913 in vivo genome edited therapeutic for Hunter syndrome, at a scientific conference later this week. Sangamo will […]
AZN lupus setback shifts focus to J&J/Lilly drugs The failure last week of the first of two Phase III studies of an AstraZeneca monoclonal antibody in systemic lupus erythematosus (SLE) – and the now assumed lower prospects for success in the second almost identical trial – looks as if it will reduce yet further the industry’s […]
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